Biochemistry of human disease Essay Example | Topics and Well Written Essays - 750 words

Biochemistry of human disease - Essay Example This hepatic dysfunction has led to jaundice as apparent from the yellowish discoloration of the while of his eyes and skin, and this has established a vicious cycle of malnutrition, alcohol intake, hepatitis, jaundice, and malnutrition. Moreover, his blood glucose level is 1.7 mmol/L (fasting reference interval, 3.0-5.5 mmol/L). In alcoholic liver disease, nutritional deficiencies are common and complicate the management. The liver disease in this patient is significant due to presence of jaundice and low blood sugars at presentation. In a habituated alcoholic, an ethanol level of 43 mmol/L or 0.2 g/dL usually does not cause stupor in contrast to that of a nonhabituated patient, where it causes impaired mental activity. Although a habituated man can remain awake even at levels >87 mmoL/L or 0.4 g/dL with the rise in the level of tolerance, usually a nonhabituated man would be stuporous at >65 mmol/L (0.3g/dL) and would lose consciousness at >87. This patient was also hypoglycemic. T hus, as expected, this man is not expected to be unresponsive with the level of alcohol at 0.36% or 80 mmol/L, and it is the hypoglycemia that has made him unresponsive. Based on this background the following questions will now be answered. About 10 percent of consumed alcohol is absorbed from the stomach, the remainder from the small intestine. Once alcohol is absorbed into the bloodstream, it is distributed to all body tissues. Because alcohol is uniformly dissolved in the bodys water, tissues containing a high proportion of water receive a high concentration of alcohol. About 90 percent of absorbed alcohol is metabolized through oxidation in the liver; the remaining 10 percent is excreted unchanged by the kidneys and lungs. In persons with a history of excessive alcohol consumption, upregulation of the necessary enzymes results in rapid alcohol metabolism. Alcohol is metabolized by two enzymes: alcohol dehydrogenase (ADH) in the

Case study (12 Questions)_Chronic Obstructive pulmonary disease Essay

Case study (12 Questions)_Chronic Obstructive pulmonary disease - Essay Example Antibiotic therapy is directed at the most common pathogens, including Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis. Mild to moderate exacerbations of COPD are usually treated with older broad-spectrum antibiotics such as doxycycline, trimethoprim-sulfamethoxazole and amoxicillin-clavulanate potassium. While doing the abovementioned management for the patient, detailed history should be done, if not obtained from the patient, from the companion. Risk factors, medications,measures done should be detailed. The vital signs of the patient should be checked constantly making sure that values are within normal. In-depth physical examination, not only of the respiratory system, but also of other systems should be done. The patient should be hooked on pulse oximeter to check for oxygenation status. Angela is also extremely distressed on arrival and asks "She is going to be all right isnt she? I know this is my fault - I wanted her to do everything – spend time with me when I knew she was busy!" Chronic pulmonary obstructive diseases is characterized by the inflammation of the lungs especially the small airways as a reaction of the body to inhaled toxins, cigarette smoke, dust and other particles due to air pollution or indoor cooking. Chronic productive cough, sputum and bronchoconstriction also result due to chronic bronchitis but ciliary dysfunctions may cause difficulties in expectorating (Devereux, 2006). The inflammation triggers a series of reactions that can lead to destruction of tissues, defense and repair mechanisms. Overworked proteases and antioxidants that fight off oxidative stress created by lung inflammation causes imbalance of these molecules in the lungs. Metalloproteases and other proteases increase due to increased number of macrophages, neutrophils, and T lymphocytes which are also involved in the pathogenesis of emphysema due to injuries in

Autism Spectrum Disorder Dissertation Example | Topics and Well Written Essays - 3000 words

Autism Spectrum Disorder - Dissertation Example The project will be using children and adults with varying degrees of ASD (Autism Spectrum Disorder). In working with children and/or adolescents the researcher must also want to work with the parents. The researcher will now devise various questions and activities that the participants may be able to do or not. This will also show the parents during their observation periods what their children can do and get a better understanding of the disorder their child has been diagnosed. This project will also need to be reliable and valid for the future, that teachers and other professionals will be able to use this project in their care of the child or children. The researcher will be conducting interviews with many different activities that will show what the participants know and teach them new skills that will help them in their life. The research will also have various questionnaires for the parents and caregivers to fill out. These questionnaires will provide sections for personal inf ormation, degree of autism, activities that they can do and skills that they cannot do, medications that they may have been on and the medications they are taking now, we will also have to know what treatments and interventions that have been used before and those that seem to work and treatments that did not work. The researcher must decide on how all these aspects of the research will progress through the study. The researcher must want to see other records that pertain to the participants of the study. The researcher must let the parents know what is going to occur throughout the study and must be given informed consent and told about confidentiality. (Corey, 2011) The researcher must need to know how the participant(s) were affected by previous treatments and medications. This study will be quantitative and qualitative for the project will be using various children and adolescents. The quantitative aspect would involve how the participants will interact (strengthen or weaken) th e effects at the different levels between the variables and the initial effects that do not change. It is also qualitative for there will be reverses to the effect depending on what occurs in the study. (Nolan.2011) Variables of this study will be the children, the parents and caregivers, and the past and future interventions that will be used and created. The researcher must also look at age, culture, grade level if school age and if working what kind of occupation they have if they are older and the independent variable being the activities that the dependent variables, the participants, will accomplish during the research process. (Cozby, 2004) Timeline for Doing Research Doing a Literature Review In doing research on Autism Spectrum Disorder the researcher must proceed with a ‘radical looking’. This is when researchers do a general literature review to see what has been done in the past and what possibly could be done in the future. When doing research, researchers must keep their ears and eyes open for new developments and suggestions that just might help to progress the research. This is when the researcher can attend conferences, listen to interviews from others about the disorder and gather information that could be used to progress the study. This can also be a time to listen for new suggestions about the disorder. This is known as ‘radical listening’

Stage 1 Essay Example | Topics and Well Written Essays - 250 words

Stage 1 - Essay Example Annual reports comprise the balance sheet, income statement, and statement of cash flows. This paper compares and contrasts the financial statements of Amazon, Apple, and eBay for the period of 2009-2013. Liquidity ratios are financial metrics used to determine a company’s ability to pay off its short-term debts obligations. A higher liquidity ratio indicates a company has a larger safety margin to cover short-term debts. The most widely used liquidity ratios are the quick ratio, current ratio, and the operating cash flow ratio. From the above analysis of the 2010-2013 financial statements of Amazon, Apple, and EBay, several comparisons on the performance of the firms can be deduced. Over the five-year period, all the three companies experience a dip in financial health. The current ratio of the three companies drops yearly from 1.33, 2.02, and 2.32 in 2009 to 1.07, 1.08, and 1.84 in 2013 for Amazon, Apple, and eBay respectively. EBay has the highest current ratio indicating that it is the financially strongest followed by Apple and then Amazon. The managers at Amazon are not generating enough returns on assets. This is indicated by the low return on assets over the five-year period. Managers at Apple are generating stable returns on assets with an average of 20% ROA over the five-year period. On the other hand, managers at eBay are generating unstable returns on assets as indicated by the volatile figures over the five-year period. Amazon’s average return on capital over the five-year period is 4% while Apple’s average return on capital is 33%. On the other hand, the average return on capital for eBay is 14%. From this figures, Apple managers at Apple are providing the highest return on capital followed by managers at eBay and finally managers at

Leadership in Nursing Essay Example | Topics and Well Written Essays - 3000 words

Leadership in Nursing - Essay Example Hence the nursing needs for the elderly have become an issue of growing concern in Hong Kong. Traditionally, the care of the sick is considered to be the moral duty of their family members among the Chinese. Hence, being cared for by nurses, who are strangers, "places the Chinese people in somewhat of a paradoxical situation" (Pang et al., cited in Smith & Tang 2004, p.18). Therefore, the success of nursing care depends also on the nurse's ability to act as a surrogate family member. With increasing health issues of the elderly and their near-total dependence on healthcare facilities, private nursing homes are increasing in demand for the confinement of the elderly with deteriorating health issues like cerebrovascular accidents, fractures such as hip fractures, congestive heart failure, chronic obstructive airways disease, dementia, parkinsonism, etc. The government has funded three forms of residential care, with the aged homes providing assistance with activities of daily living, C&A homes providing personal attention and some nursing care, and infirmaries providing more intensive nursing care with medical supervision (Bartlett & Phillips 1995, p.238). Though several measures have been undertaken to increase the number of residential care homes, the availability of such care homes unfortunately still fall short of demand. This places increasing responsibility on the available nursing care personnel. According to a study done by Leung et al... Though several measures have been undertaken to increase the number of residential care homes, the availability of such care homes unfortunately still fall short of demand. This places increasing responsibility on the available nursing care personnel. According to a study done by Leung et al. (2000, p.65) from a random sample of private nursing homes in Hong Kong East region, increasing number of bedridden or chairbound patients, increasing dependency for basic activities of daily living, increasing problems of incontinence of bowel and/or bladder, increasing use of supporting devices, aggravating problems of bedsore, etc. lead to more hospitalizations and specialist out-patient clinic visits. Unfortunately the incidences of re-hospitalizations of these patients with recurrences of the same disease conditions have been gaining in frequency recently. "Frail elderly patients are shuffled back and forth between acute care, non-acute care, old age homes and the community" (Derrick 1998, p.1). This situation calls for a highly efficient and totally effective nursing care system. This report studies the scenario in a private nursing home in Hong Kong. The scenario is analysed for the effectiveness of the nursing care rendered by the present nursing team, its leadership style, and its advantages and disadvantages. Also studied are the different leadership styles and concepts that are applicable to this context. New strategies for improving the situation are developed, and appropriate leadership skills are recommended that suit these strategies. 2. Context I work as intern in a nursing team handling 100 inhabitants of a private nursing home in Hong Kong. The average age of the group is

Assignment 2 Essay Example | Topics and Well Written Essays - 500 words - 10

Assignment 2 - Essay Example The insole and outsole are fitted with cork, allowing foot to form its own foot-bed for custom support. The shoes are durable and very fashionable. The advantage of buying the shoes was that it was worth the price, it was comfortable and available in a range of colours. The newspaper covered the topics that I liked reading. The disadvantage of the phone was that it was slightly expensive with poor camera quality. I was satisfied with the The Wall Street Journal newspaper because of how widely it featured its news from political scenes, business news and entertainment. However, I was dissatisfied with the purchase of the Samsung Galaxy S4 phone because the camera was not good for low-light shots, it had no Fm radio and the internal storage was limited because of the many applications. I intend to continue with the purchase of the newspaper and the shoes but for the phone, I will try another model like Nokia. My dad has one and its camera is great with low-light shots, it also has different designs, which give it exciting looks. According to Ramaswamy (2012), the first stage is needing identification. When I needed a phone, I choose the Samsung Galaxy phone after listening to my classmates. There were different phone models, but most of them recommended the Samsung phone because of its features. Thereafter, I started to process the information, which was further stimulated by watching television that evening, featuring an advert of the phone. Seth (2011) refers to this stage as information search and processing. I engaged in elaborate processing, by paying attention to the information available about the phone. I thought about the likely advantages and disadvantages of using it. When the information was processed and secured, I figured out other phone models, their features and where possible to get them. According to Ramaswamy (2012), this stage involves identification and evaluation of

Analog Circuit Computer Aided Design (CAD) Essay

Analog Circuit Computer Aided Design (CAD) - Essay Example This section deals with the existing literatures related to analog circuit optimization. It outlines a summary of all the resource materials, authorial credentials, content credibility, source credibility, text credibility- Fluid integration of the source evaluation. A true literature review gives the proper sense of works that technology has achieved till date into that specified topic which helps one researcher to bring down his own research problem. Han Young et al. (1990) developed an analog silicon compilation system for CMOS op amps (OPASYN). The synthesis starts from a certain specification. From its database, program selects op amp topology that suits most with the given specification. Using parametric optimization the circuit then determines optimal value for its parameters. It also produces Design-Rule-Correct compact layout of the optimized op amp. Yang et al. (1995) proposed a Simulated Annealing (SA) algorithm for topology selection and sizing. In analog cells, topology choice and sizing simultaneously is efficient than normal two step mode synthesis. Basic problem with that approach is that super circuits must be worked out for each sort of analog cells. Chen et al. (2000) placed an iterative optimization idea for improving delay in digital circuit. Instead of only adjusting that gate sizes to reduce delay, they adjusted wire loads of the gates by repositioning them using geometric program. It gave better result in deep sub-micron design where the effect of interconnect delays dominates Mandal P and Visvanathan V (2001) devised an efficient technique for sizing of op amp by sequential convex optimization problem. This method then prototyped in MATLAB to apply into CMOS two stage op amp.