Wednesday, June 19, 2019

Biochemistry Research Essay Paper on MUcolipidoses Diseases ( EXPLAIN

Biochemistry Essay on MUcolipidoses Diseases ( EXPLAIN BRIEFLY) - Research Paper ExampleMucolipidosis type 1 (ML 1) known as sialidosis occurs because of a lack in sialidase, a critical digestive enzyme. According to Smith, (2013) the rare sickness is an inheritation of a defect involving storehouse by lysosomes. For the cells to function properly glycoproteins should be throw in the towel from molecules that have sugar content. Sialidase in particular assists in removing sialic acid from forms of sugar proteins (Miedel, 2008). Due to the deficiency of the enzyme, results in molecular that resemble sugar settling in not only the cells but also the neurons and the bone marrow. The body of the individuals becomes incapable of fighting infections. The defect is quite similar to mucopolysaccharidoses.Mucolipidosis 2 alpha or beta, is a disease that interferes with diverse body parts to the extent of killing the victims. Patients had some phase-dense intracytoplasmic content in the fi broblasts creating incusion in the cell (Vuong & Berry, 2002). Studies indicate that individuals with the defect do not make it to the teenage. Mucolipidosis type 3 is quite similar to Mucolipidosis type 2 in that it affects many body parts. Mucolipidosis type 3 involves a deficiency of N-acetylglucosamine-1-phosphotransferase (Smith, 2013). The enzyme is implemental as it focuses on the carbohydrates in the glycoproteins. The absence of the enzyme makes the glycoproteins to get stored outside the lysosomes.Type 4 results from autosomal and recessive genetic disorder. As part of the defects that involve the storage of components in the lysosomes, ML 4 entails the inability of body cells to manufacture enzymes necessary for breaking down various components (Agarwal & Gass, 2012). The body becomes unable to transfer lipids as head as other materials in the cells. This leads to the lipids to settling within the body as well as the cells (Miedel, 2008). Both the brain and the nervous system suffer because of the disease thereby reducing the life

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